Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-binding capacity. and for regulating platelet function in health and disease. Platelets derived from megakaryocytes are small anucleate cells in peripheral blood. with the ability to rapidly adhere. https://www.roneverhart.com/Echo-Fix-EF-P2-Spring-Reverb-Pedal-p32083/