Abstract Clearance of protein waste products from the brain is accomplished by a combination of advection and diffusion in cerebrospinal fluid (CSF) and interstitial fluid (ISF). In the glymphatic model. there is a flow of ISF in the interstitial space. and both advection and diffusion occur there. https://www.roneverhart.com/Taylor-AD24ce-American-Dream-Acoustic-Electric-Guitar-Shaded-Edgeburst-p19272/